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How Does Ketamine Affect the Brain?

Ketamine is gaining traction in the news as a new, upcoming treatment for depression, anxiety, chronic pain, and other select debilitating conditions along with their associated symptoms. This leaves many people to wonder exactly how Ketamine works and what the effect on the brain may be. During Ketamine infusions, the brain receives profound effects. Brain cell connectivity is promoted and sustained with Ketamine therapy, thereby reversing the effects of chronic stress. In this article, we will take a closer look at how Ketamine affects the brain and to answer the question – what is Ketamine used for?


What Part of the Brain Does Ketamine Affect?

Ketamine therapy blocks NMDA (N-methyl-D-aspartate), which is a glutamate receptor. This excitatory neurotransmitter is responsible for making neurons more active, and for creating a more communicative system that allows new connections to be made. At first thought, it might appear that blocking this receptor should deprive the brain of the necessary signals, but that’s not the case at all with patients who suffer from depression or anxiety. Instead, Ketamine treatment appears to awaken their neural activity as a result of the blockage.

Clinical Trials Showing the Benefits of Ketamine

Several clinical trials have been conducted over the years to determine the effectiveness of Ketamine when administered to patients who suffer from treatment-resistant depression and chronic pain. These trials have proven that Ketamine effectively reduces debilitating symptoms associated with depression, anxiety and chronic pain. The success of Ketamine clinical trials has led to certain forms of Ketamine, such as esketamine (administered by nasal spray), getting approved by the FDA. Upon further testing, more forms of Ketamine should get approved in the near future as the benefits are undeniable. Look at the results of these clinical trials from the NIMH and Columbia University:

2018 - Clinical Trial Provided by National Institute of Mental Health (NIMH) - https://clinicaltrials.gov/ct2/show/results/NCT00088699

2019 - Clinical Trial Provided by Columbia University - https://clinicaltrials.gov/ct2/show/NCT01558063

How Does Ketamine Affect the Brain?

So, what does Ketamine do exactly? Why should someone use Ketamine for pain or depression? Part of the many benefits from Ketamine infusions includes creating new brain cell connectivity, which reverses the effects of depression and chronic stress. When a person undergoes chronic pain or stress, the brain’s circuits change. To reverse these effects, Ketamine allows for new connections to be made. In this process, the symptoms of depression, anxiety, and suicidal thoughts begin to dampen then, in some cases, disappear. Once treatment begins, Ketamine can act fast. Brain studies have shown that the benefits of Ketamine treatment can be seen in as little as a few hours post-treatment.

Ketamine: A Known Anesthetic with a New Purpose

For many years, Ketamine has been regarded as a great option for anesthesia. When used in this way, the dosage is much higher than the dosage in Ketamine infusions used for pain, depression or anxiety. The FDA has since recognized the benefits of Ketamine for chronic pain and depression, which is why the organization has approved one form of Ketamine for use in these situations. Considering that the World Health Organization now recognizes depression as the leading cause of disability worldwide, it’s refreshing to see such an effective treatment option available and approved. While Ketamine was only used as an anesthetic at one time, new research suggests that there is a multitude of other benefits. We’ve seen, firsthand, the rapid reversal of symptoms of chronic pain, anxiety, and depression; because of this, and our passion to assist Military Veterans in their civilian life, we highly recommend Ketamine infusions for pain control and other serious conditions.

Ketamine Infusion Therapy in Colorado Springs

Many people wonder - how long does Ketamine last? Unfortunately, there isn’t a set answer to this as everyone responds to treatment differently. What we do know is that Ketamine pain management and treatment for depression is effective and an outstanding solution so you can stop suffering. At the Military Matters Ketamine Clinic, we provide Ketamine infusions to help you. We are located in the Mt. Carmel Veterans Service Center in Colorado Springs. Our primary focus is serving Military Veterans. We know that you suffer from depression, anxiety and pain, which is why we want to provide the best treatments for you. With Ketamine, you don’t have to give up one more day of your life to these issues. We are happy to serve the broader Colorado Springs community with Ketamine infusion therapy. Our goal is to improve the life of anyone suffering from these unmanageable symptoms. If you have depression, anxiety or pain, set up your appointment for a consultation today.

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