We are now accepting new patients, to schedule an appointment, please call us at 719-671-3147

How Ketamine Differs From Antidepressants

Depression is a serious mental health condition that affects millions in the United States. Unfortunately, about 30% of individuals diagnosed with depression fail to respond to treatment with traditional antidepressant medication. When they do work, these medications can take months to provide tangible relief from your symptoms. Ketamine is different.  

Our expert team at Military Matters Ketamine Clinic in Colorado Springs, Colorado, sponsored by Mt. Carmel Veterans Service Center, specializes in treating military veterans who are experiencing the debilitating effects of mental health disorders such as depression.  

Learn what makes ketamine therapy different and why we find it an effective alternative to traditional antidepressant medications.

Traditional antidepressants vs. ketamine

SSRIs (selective serotonin reuptake inhibitors) are typically the first choice in medication therapy for depressive disorder. SSRIs, which include Prozac®, Lexapro®, Zoloft®, and Paxil®, increase your serotonin levels to correct chemical imbalances in your brain. Unfortunately, this strategy is not effective for everyone because not all depression is due to low levels of serotonin. 

Ketamine takes a completely different approach to treating depression. Instead of focusing on the chemical imbalance in your brain, it repairs the existing damage caused by long-term stress.

Stress and depression

Stress causes your body to produce high levels of hormones like cortisol. Long-term stress causes these powerful substances to build up in your brain as proteins. These changes can alter the neurons in your brain, making them less adaptable and interfering with their ability to communicate with other neurons.

As a result, you can have a harder time dealing with negative life events, which can complicate depression and anxiety symptoms. Ketamine can repair this damage and help regrow broken connections. When used as part of a comprehensive treatment plan, ketamine can also create new neural pathways and protect you from having future symptoms of depression.

Ketamine therapy has proven clinically effective for a variety of issues, including treatment-resistant depression, PTSD, anxiety, obsessive-compulsive disorder, and chronic pain conditions such as fibromyalgia.

Effective and fast

Traditional oral antidepressants are taken daily, and it may take 4-6 weeks to several months for these medications to positively affect your serotonin levels.

At Military Matters, we deliver ketamine therapy via intravenous (IV) infusion. These sessions can offer an antidepressant effect within a few hours. A series of ketamine infusions over several weeks, followed by periodic “maintenance” infusions as necessary, can provide long-term relief from depression and its debilitating effects on your health and well-being.

To learn more about ketamine, call our office in Colorado Springs or request a phone meeting online. We’re here to help.

You Might Also Enjoy...

Think You Know Ketamine? Think Again

First used in the field during the Vietnam War, ketamine is proven in pain relief and also showing promise as a treatment for depression. Thought to work by rewiring your brain, low doses of the drug are safe for use under clinical conditions.

PTSD: How Ketamine Offers Relief

If you experienced trauma during combat or another violent incident, the effects can stay with you long after the event has passed. PTSD can haunt you and leave a lasting impact on your mental health -- but ketamine therapy can help.

What to Expect During Your Ketamine Therapy

Have you heard about ketamine therapy for chronic pain and/or depression, PTSD and other mental health conditions? Have you wondered what to expect during and after a session? Learn what the experts say about medically managed ketamine therapy.